产品货号：
Z11366
中文名称：
ATG12抗体
英文名称：
Anti-ATG12 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ATG12 Antibody |
| 指标别名 | APG12;APG12 like;APG12L;ATG12;Autophagy related protein 12;FBR93;HAPG12;Ubiquitin like protein ATG12 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | ATG12 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ATG12 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human ATG12.The immunogen is located within the first 50 amino acids of ATG12. |
| 计算分子量 | 15kDa |
| 成分 | ATG12 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ATG12 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Autophagy,the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells.It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components.This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1.ATG12,another member of the autophagy protein family,forms a conjugate with ATG5;this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy.This conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1),inhibiting type I interferon production and permitting viral replication in host cells.ATG12 has also been shown to interact with ATG10 in human embryonic kidney cells in the presence of ATG7.At least two isoforms of ATG12 are known to exist. |
| Uniprot ID | O94817 |
| 基因名全称 | ATG12 autophagy related 12 homolog (S.cerevisiae) |
| 蛋白名全称 | ATG12 autophagy related 12 homolog (S.cerevisiae) |
| 推荐稀释比 | ATG12 antibody can be used for the detection of ATG10 by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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